To record the compound action potential of the median nerve intraoperatively, where should the electrode be placed?

The compound action potential (CAP) of the median nerve is best recorded from the antecubital fossa. This area is where the median nerve is relatively superficial and its electrical activity can be effectively captured. During intraoperative monitoring, placing the electrode in this location allows for optimal access to the nerve's pathway, maximizing the quality of the signal obtained while minimizing interference from other anatomical structures.

Recording from the wrist may not provide as clear a signal since it is farther from the nerve's location relative to the axons that are actively conducting action potentials. Similarly, placing the electrode at C2 or the shoulder would be inappropriate for capturing the CAP of the median nerve, as these areas are not anatomically aligned with the pathway and function of the median nerve. Proper electrode placement is crucial for accurate monitoring and interpretation of neuromuscular function during surgery, which reinforces the significance of choosing the antecubital fossa for this specific recording.