What is the gain of an amplifier set to yield an output signal of 1 volt for an input signal of 10µV?

To determine the gain of an amplifier, you can use the formula:

[ \text{Gain} = \frac{\text{Output Voltage}}{\text{Input Voltage}} ]

In this scenario, the output signal is 1 volt and the input signal is 10 microvolts (10µV), which is equivalent to 0.00001 volts. By substituting these values into the formula:

[ \text{Gain} = \frac{1 , \text{volt}}{10 , \mu\text{V}} = \frac{1 , \text{volt}}{0.00001 , \text{volts}} = 100,000 ]

Thus, the gain of the amplifier that yields an output of 1 volt for an input of 10µV is indeed 100,000. This high gain is often necessary in neurophysiologic intraoperative monitoring to amplify small biological signals that are typically measured in microvolts, allowing for clearer and more detectable readings during procedures.